 |
 |
| |
NATIONAL
ESSENTIAL DRUGS LIST. |
|
NATIONAL
ESSENTIAL DRUGS LIST
THIRD REVISION
1.1
General Anaesthetics and Oxygen
1.2
Local Anaesthetics
1.3
Neuromuscular Blocking Agents
1.4
Miscellaneous
2.1
Opioid Analgesics
2.2
Non-Opioid Analgesics and NSAIDS
5:
ANTIINFECTIVE DRUGS
5.1
Anthelmintics
5.2
Antibacterials
5.3
Antituberculosis Drugs
5.4
Antifungal Drugs
5.5
Antiamoebic Drugs
5.6
Antiviral Drugs
5.7
Antimalarial Drugs and Prophylactics
5.8
Antileishmanial Drugs
6:
ANTIMIGRAINE DRUGS
7:
ANTIPARKINSONISM DRUGS
8:
DRUGS AFFECTING BLOOD
8.1
Antianaemic Drugs
8.2
Drugs Affecting Coagulation
9:
BLOOD PRODUCTS AND PLASMA SUBSTITUTES
10:
CARDIOVASCULAR DRUGS
11:
DERMATOLOGICAL DRUGS
12:
DIURETICS
13:
GASTROINTESTINAL DRUGS
14:
HORMONES, OTHER ENDOCRINE DRUGS AND
CONTRACEPTIVES
15:
IMMUNOLOGICALS
15.1
Diagnostics
15.2
Sera and Immunologicals
15.3
Vaccines for Universal Immunization
15.4
Vaccines for Specific Use
15.5
Immunosuppressants
16:
MUSCLE RELAXANTS (PERIPHERALLY ACTING)
AND CHOLINESTRASE INHIBITORS
17:
OPHTHALMOLOGICAL PREPARATIONS
17.1
Antiinfective Agents
17.2
Miotics and Antiglaucoma Drugs
17.3
Mydriatics and Cycloplegics Drugs
17.4
Corticosteroids
17.5
Non-steroidal Antiallergic/Decongestants
17.6
Topical Anaesthetics
17.7
Others
18:
OXYTOCICS AND ANTIOXYTOCICS
19:
PERITONEAL DIALYSIS SOLUTION
20:
PSYCHOTHERAPEUTIC DRUGS
21:
DRUGS ACTING ON THE RESPIRATORY TRACT
22:
SOLUTIONS CORRECTING WATER, ELECTROLYTE
AND ACID BASE
DISTURBANCES
23:
VITAMINS AND MINERALS
24:
E.N.T. PREPARATIONS
25:
ANTISEPTICS AND DIS-INFECTANTS
25.1
Antiseptics
25.2
Disinfectants
26:
DENTAL PREPARATIONS
27:
DISPENSARY ITEMS
28:
DRUGS FOR LOCAL PURCHASE
28.1
Antidotes and other substances used in poisoning
28.2
Antileprosy Drugs
28.3
Antineoplastics, Immunosuppressives and Drugs
used in palliative care
28.3.1
Immunosuppressive Drugs
28.4
Diagnostic Agents
29: DRUGS
FOR SPECIALIZED CENTERS
29.1
Antiretroviral Drugs
PREFACE
After
the second World War the development and emergence of miracle
drugs like antibiotics brought a revolution in the medical care.
The obvious effectiveness of these new pharmaceuticals and intensive
marketing efforts combined to catalyze wide spread use of modern
medicine. A rapidly growing and profitable industry, together
with an enthusiastic but largely uninformed audience and an
unregulated market, resulted in excess of promotion and consumption
alowgwith inflated level of expenditure. However, by 1970s it
had become clear that least advantageous nations were not even
meeting the basic needs of their people for essential life saving
and health promoting drugs. As a result gradually a number
of countries started concentrating on the development of a basic
list of reliable drugs to meet the most vital basic needs of
their people.
A World
Health Organization (WHO) Committee of Experts met in 1977 to
determine the number of drugs, which were actually needed to
ensure a reasonable level of health care for as many people
as possible. Consequently, the first Model List of Essential
Drugs was finalized in the same year. This list is being updated
regularly by the WHO and is intended to be used as a guideline
and provide basis for member countries to identify their own
priorities and make their own selection. Through 1970s and 1980s
the WHO started promotion of the concept of Essential Drugs
Program in order to redress this imbalance. The program aimed
at reduction in the number of drugs purchased/used by the hospitals/institutions
to a minimum possible level in order to make best use of limited
public funds.
Essential
drugs as defined by WHO are those that satisfy the health care
needs of majority of the population. They should therefore be
available at all times in adequate amounts and in the appropriate
dosage forms.
The National
Essential Drugs List (NEDL) of Pakistan was first prepared in
1994 in consultation with relevant experts. The list was previously
reviewed in 1995 and 2000. The present list is the third revision
containing 452 drugs of different pharmacological classes.
The health
sector in general and public health sector in particular is
expected to seriously consider adopting this list. The provincial
health departments can play a pivotal role to encourage the
hospitals/institutions for making bulk purchases from within
this list. We hope that this list will find more acceptance
among health care professionals.
Maj.
Gen. ® Mohammad Aslam HI (M)
Director General
Health
EXPLANATORY NOTES
Letters in parentheses following
drug names indicate: (P) for Primary,
(S) for Secondary and (T)
for Tertiary.
1.
Classification of drugs for use at various levels of Health
Services is as follows:
(P)
PRIMARY:
For use at the Primary Health Care Level including Basic Health
Units and Rural Health Centers.
(S)
SECONDARY:
For use at the Secondary Health Center Level i.e; hospitals.
(T)
TERTIARY:
For use at the specialized and sub-specialized levels for specific
expertise diagnostic precision or special equipment required for
proper use.
II.
Drugs subject to international controls under :
(1)
Single Convention on Narcotic drugs 1961:
(2)
Convention on Psychotropic Substances 1971; and
(3)
Convention on Illicit Traffic in Narcotic Drugs and Psychotropic
Substances 1988.
III.
Special considerations ;
(4)
In renal insufficiency, contraindicated or dosage adjustments
necessary;
(5)
To improve compliance;
(6)
Special pharmacokinetic properties;
(7)
Adverse effects diminish benefit/risk ratio;
(8)
Limited indications or narrow spectrum of activity;
(9)
For epidural anaesthesia;
(10) Specific
expertise, diagnostic precision, individualization of dosage
or special equipment required for proper use;
(11)
Monitoring of therapeutic concentrations in plasma can improve
safety and efficacy;
(12)
COMPLEMENTARY DRUGS: Choice to be made on the basis
of cost effectiveness.
IV.
When the strength of a drug is specified in terms of
a selected salt or ester, this is mentioned in brackets; when
it refers to the active moiety, the name of the salt or ester
in brackets is preceded by the word ‘as’.
ANAESTHETICS
1.1 General
Anaesthetics and Oxygen
|
diazepam (P),
(S), (T), (2) |
10mg/2ml inj. |
|
ether,
anaesthetic (P), (S), (T), (3,10) |
liquid for
inhalation |
|
halothane (T)
(10) |
liquid for
inhalation |
|
|
50 mg/ml
inj.(as hydrochloride) |
|
|
gas for
inhalation |
|
(*propofol |
10 mg/ml inj) |
|
thiopental
(T), (10) |
500 mg powder
for inj. (as sodium salt) |
|
|
1.2 Local
Anaesthetics
|
|
|
|
|
50 mg/ml Inj. |
|
lignocaine
(S), (T) |
|
|
|
|
|
|
|
|
|
2%
(hydrochloride) gel. |
|
|
|
|
|
1:100 000 inj. |
|
|
|
|
|
1:200 000 inj. |
|
|
|
|
|
1:80 000 dental cartridge |
1.3
Neuromuscular Blocking Agents.
|
atracurium (T) |
25&50 mg inj.
(as besylate) |
|
pancuronium
(T) |
4 mg inj. (as
bromide) |
|
suxamethonium
(T), (10) |
100 mg inj.
(as chloride) |
|
|
|
1.4
Miscellaneous
|
atropine (P),
(S), (T) |
1mg inj. (as
sulfate) |
|
|
gas for
inhalation. |
2:
ANALGESICS, ANTI TIPYRETICS, NON-STEROIDAL
ANTI-INFLAMMATORY
DRUGS AND DRUGS
USED TO TREAT GOUT.
2.1 Opioid
Analgesics
|
|
|
|
|
|
|
pethidine (P),
(S), (T), (1,4) |
|
2.2
Non-Opioid Analgesics and NSAIDS
acetylsalicylic acid (P), (S), (T) 300
mg tab.
diclofenac (T) 75
mg / 3 ml inj. (as sodium)
ibuprofen (P),(S),(T) 200,400
and 600 mg tab.
indomethacin (P),(S),(T) 25
mg cap or tab.
paracetamol (P),(S), (T)
500 mg tab.
2.3
Local Analgesics
choline
salicylate (P), (S), (T) 8.7%
gel for local use.
2.4
Drugs used to treat Gout
|
allopurinol
(S), (T), (7) |
100 & 300 mg
tablet |
|
colchicine
(S), (T), (4) |
0.5 mg tab |
3:
ANTIALLERGICS AND DRUGS USED IN
ANAPHYLAXIS
|
adrenaline
(P), (S), (T) |
1mg inj. (as
hydrochloride) |
|
|
|
|
dexamethasone
(P), (S), (T) |
|
|
hydrocortisone
(P),(S),(T) |
|
|
prednisolone
(P), (S), (T) |
5 mg tablet |
|
promethazine
(P), (S), (T) |
|
|
|
|
4:
ANTI-EPILEPTICS
|
|
200 mg tab.
Syp. |
|
diazepam
(P), (S), (T) (2) |
10 mg/2ml
injection. |
|
ethosuximide
(T) |
250 mg
capsule/tab. 250 mg/5ml syrup. |
|
|
30 mg tab. 200
mg/ml inj. |
|
|
100mg tab./capsule (as sodium) |
|
|
30mg/5ml syrup
(as sodium) |
|
|
|
|
|
|
|
|
250 mg/5ml
syrup). |
5:
ANTI-INFECTIVE DRUGS.
5.1
Anthelmintics
|
|
|
|
|
|
|
|
40
mg/5ml syrup. |
|
|
|
|
niclosamide(P),
(S), (T) |
500
mg tab. |
|
pyrantel
(P), (S), (T) |
250
mg tab. (as pamoate) |
|
|
250
mg/5ml susp.(as pamoate). |
5.2 Antibacterials
|
|
250 & 500 mg capsule/tablet (as
trihydrate).
125 & 250
mg/5ml syrup (as trihydrate) |
|
|
250 & 500mg
tab/cap (as anhydrous/trihydrate)
125 mg/5ml syrup (as anhydrous/trihydrate)
500mg inj.(as
sodium salt). |
|
amikacin
(T) |
|
|
benzylpenicillin
(P), (S), (T) |
100.44 gm inj.
(benzathine)
600 mg (1
million IU) inj.
|
|
cefazolin
(T) |
250,500mg &
1gm inj.(as sodium salt) |
|
|
|
|
|
|
|
ceftizoxime
(T) |
|
|
cefixin
(T) |
100 mg cap. |
|
|
125,250 mg
tab. (as axetil)
|
|
|
250 & 500 mg
cap.
|
|
cephradine
(T) |
250 & 500 mg
cap.
125 mg/5ml &
250 mg / 5ml syrup
|
|
|
125mg/5ml
syrup (as palmitate)
|
|
|
|
|
|
|
|
|
250 mg cap.
(as sodium)
250 mg inj.
(as sodium) |
|
|
|
|
|
|
|
doxycycline
(T), (5,6) |
|
|
erythromycin
(P), (S), (T) |
|
|
|
|
|
|
500mg inj. (as
lactobionate). |
|
|
40 & 80 mg inj.
(as sulfate) |
|
|
200, 400 mg
tab. |
|
|
|
|
|
500 mg/100ml vial. |
|
nalidixic
acid (P), (S), (T) |
500 mg tablet |
|
|
300 mg / 5ml
syrup.
5000,000 IU
tab |
|
|
100,000 IU/ml
drops |
|
|
100,000 IU
pessaries |
|
nitrofurantoin
(P), (4,8) |
100 mg |
|
nystatin
(S), (T) |
200 mg tab.
(as hydrochloride) |
|
pefloxacin
(T) |
400 mg/5ml inj. |
|
phenoxymethylpenicillin
(P), (S), (T) |
250
& 500mg tab. (as potassium salt) 125
mg/5ml syrup.
|
|
procaine
benzylpenicillin (P), (S), (T) |
1 & 3 million
IU inj. |
|
sulphasalazine
(S), (T) |
500 mg tab. |
|
tinidazole
(S), (T) |
300 & 500 mg
tab. |
|
trimethoprim
(S), (T), (8) |
300 mg tab. |
5.3
Anti-Tuberculosis Drugs
|
ethambutol
(P), (S), (T), (4) |
400mg
tab.(hydrochloride) |
|
isoniazid
(P), (S), (T) |
50, 100 & 300
mg tab. Syrup. |
|
isoniazid
+ ethambutol (P),(S),(T),(5) |
150 mg +400 mg |
|
pyrazinamide
(P), (S), (T) |
500 mg tab. |
|
rifampicin
(P), (S), (T) |
150, 300,
450 & 600 mg tab/cap syrup. |
|
rifampicin
+ isoniazid (P),(S),(T) |
150 mg + 100
mg tab./cap. |
|
|
300 mg + 150
mg tab./cap. |
|
|
450 mg + 300
mg tab./cap. |
|
rifampicin
+ isoniazid + pyrazinamide (P),(S),(T),
(5)
|
150
mg + 75 mg + 400 mg |
|
rifampicin
+ isoniazid + pyrazinamide + ethambutol
(P),(S),(T) |
150 mg + 75 mg
+ 400 mg + 275 mg |
|
streptomycin
(P), (4) |
1g inj. (as
sulphate). |
|
thioacetazone
(P), (S), (T) |
50mg tab. |
|
thioacetazone
+ isoniazid (P), (S), (T), (7) |
(50 mg + 100
mg) tab. (150 mg + 300 mg) tab |
5.4
Anti-Fungal Drugs
|
amphotericin
B (T), (4) |
50 & 100 mg
tab. |
|
griseofulvin
(T), (7,8) |
125 & 500 mg
tab. |
|
ketoconazole
(T) |
200 mg tab.
100 mg/5ml oral suspension |
|
nystatin
(P), (S), (T) |
500 000 IU
tablets |
|
|
100 000 IU/ml
oral drops |
|
|
100 000 IU
pessary |
5.5
Anti-Amoebic Drugs
|
chloroquine
(P), (S), (T) |
150mg tab (as
sulphate or phosphate) |
| |
50
mg/5ml syrup, 200 mg inj.
|
|
diloxanide
(P), (S), (T) |
500 mg tablet
(as furoate). |
|
metronidazole
(P), (S), (T) |
200 & 400 mg
tab. |
|
|
200 mg (as
benzoate)/5ml suspension. |
5.6 Antiviral
Drugs
|
acyclovir
(T), (8) |
200 mg tab
250mg inj. (as sodium) |
5.7
Antimalarial Drugs and Prophylactics
|
chloroquine
(P), (S), (T) |
150mg tab (as
sulphate orphosphate) |
|
|
50mg/5ml
syrup&200 mg inj. |
|
primaquine
(P), (S), (T) |
7.5 mg tab. |
|
quinine (P),
(S), (T) |
200 mg tab.
(as sulphate) |
|
|
300 mg tab.
(as bisulphate) |
|
quinine
dihydrochloride (S),(T) |
600mg inj |
|
sulphadoxine +
pyrimethamine (P), (S), (T) |
500 mg + 25 mg
tab. |
5.8
Antileishmanial Drugs
|
sodium
stibogluconate (S) |
100 mg inj. |
6:
ANTIMIGRAINE DRUGS
|
ergotamine
(P), (S), (T), (7) |
1mg tab. (as
tartarate)
0.5mg inj. |
7:
ANTIPARKINSONISM DRUGS
|
biperiden (P),
(S), (T) |
2 & 5 mg inj.
(as lactate) |
|
carbidopa+levodopa (T),(5,6) |
25 mg + 250 mg
tab. |
|
procyclidine
(S), (T) |
5 mg. tab. |
|
selegiline (T) |
5 mg tab. |
8:
DRUGS AFFECTING BLOOD
8.1
Antianaemic Drugs
|
ferrous salt
(P), (S), (T) |
eq.to 60 mg
iron tab. eq.to 25mg iron/ml syrup (as sulfate). |
|
folic acid
(P), (S), (T), (10) |
1 & 5mg tab. |
|
iron dextran
(P), (S), (T), (5) |
eq. to 50mg
iron/ml inj. |
8.2 Drugs
Affecting Coagulation
|
heparin (S),
(T) |
1000, 5000 &
20,000 IU inj.
(as sodium) |
|
phytomenadione
(S), (T) |
10 mg inj.
10mg tab. |
|
tranexamic
acid (S),(T) |
250mg cap. 250
mg inj. |
|
warfarin (S),(T),
(6,10) |
1 & 5 mg tab.
(as sodium) |
9: BLOOD
PRODUCTS AND PLASMA SUBSTITUTES
|
albumin
(human) (T) |
5% & 25%
solution for inj. |
|
dextran 40
(P), (S),(T) |
40% w/w for
infusion. |
|
factor VIII
concentrate (T), (8,10) |
inj. |
|
factor IX
complex |
inj. |
|
conc. USP (T) |
|
|
immune human
serum (T) |
inj. |
|
platelets
human (T) |
inj. |
|
polygeline (T) |
35% inj. |
10:
CARDIOVASCULAR DRUGS
|
acetylsalicylic acid(P), (S), (T) |
150 mg, 300 mg
tab. |
|
amiodarone (T) |
200 mg tab. |
|
amlodipine
(S), (T) |
5 mg tab. |
|
atenolol (S),
(T) |
50 & 100 mg
tab. |
|
captopril (T) |
25 & 50 mg
tab. |
|
digoxin (P),
(S), (T), (4) |
500 mcg inj.
250 mcg tab. |
|
|
50 mcg/ml oral
solution. |
|
diltiazem (T) |
30, 60, 90 &
180 mg tab. |
|
|
(as
hydrochloride) 10 & 50 mg inj. |
|
dobutamine (T) |
250 mg inj. |
|
dopamine (S),
(T) |
200 & 800 mg
inj. (as
hydrochloride) |
|
(enalapril
(S), (T) |
5 & 10 mg
tab), 100 mg inj). |
|
esmolol (T) |
100 mg inj. |
|
gemfibrozil
(T) |
300 mg cap. |
|
hydralazine
(T) |
25 mg tab. 20
mg inj. |
|
isoprenaline
(S), (T) |
30 mg tab. 1mg
inj. |
|
isosorbide
dinitrate (P), (S), (T) |
5mg tab (sublingual).
10mg tab. |
|
labetolol (T) |
100 & 200 mg tab. (as
hydrochloride) |
|
|
5mg/ml inj.
(as hydrochloride). |
|
lignocaine
(P), (S), (T) |
1% & 2% inj.
(as hydrochloride). |
|
(lisinopril |
5, 10 & 20 mg
tab) |
|
losartan (S),
(T) |
25 mg tab. |
|
methyldopa
(P), (S), (T), (7) |
250 & 500 mg
tab. |
|
|
250 mg inj. |
|
nicotinic acid
(S), (T) |
50mg tab. |
|
(nitroglycerin
(P), (S), (T) |
500 mcg tablet
(sublingual) |
|
|
2.6 & 6.4 mg
tab. |
|
|
5&10 mg
patches) |
|
|
1mg/ml I.V. infusion (T) |
|
phenytoin (S),
(T) |
30 mg/5ml susp. |
|
|
25 mg cap.
(sodium) |
|
|
250 mg inj. |
|
prazosin (P),
(S), (T) |
1 & 2 mg tab. |
|
procainamide
(T) |
250 mg tab.
100 mg inj. |
|
propranolol
(P), (S), (T) |
10, 40, 80 &
160 mg tab. |
|
|
1mg inj. |
|
quinidine (T) |
200 mg tab.
(as sulphate) |
|
sodium
nitroprusside (T), (8,10) |
50 mg inj. |
|
verapamil (S),
(T), (8,10) |
40, 80 & 240
mg tab. 5mg inj. (T) |
11:
DERMATOLOGICAL DRUGS (TOPICAL)
|
benzoic acid +
salicylic acid (P), (S), (T) |
6% + 3%
ointment or cream |
|
benzoyl
peroxide (T) |
5% & 10% gel |
|
benzyl
benzoate (P), (S), (T) |
25% lotion |
|
betamathosone
(S), (T) |
0.1% oint/cream/lotion |
|
betamathosone
+ neomycin (S), (T) |
0.1+0.5% oint/cream/lotion |
|
benzophenones
(T) |
cream/lotion/gel |
|
calamine
powder (P), (S), (T) |
for 15%
calamine lotion |
|
clotrimazole
(P), (S), (T) |
1% cream/oint/solution |
|
coaltar liquid
(P), (S), (T) |
for 7.5%
lotion. |
|
gammabenzene
hexachloride (S), (T) |
1% cream |
|
gentian violet
(P), (S), (T) |
0.5% aq.
solution |
|
hydrocortisone
(P), (S), (T) |
1% cream/oint
(as acetate) |
|
hydrocolloid
methoxasalen (S), (T) |
dressings |
|
|
10 mg tab. |
|
|
0.75% oint./cream/lotion. |
|
neomycin+bacitracin (P), (S), (T) |
5mg neomycin
sulfate |
|
|
+500 IU
bactitracin zinc/g
|
|
neomycin (P),
(S), (T) |
0.5% oint/cream |
|
nystatin (P),
(S), (T) |
100,000 iu/gm
oint/cream |
|
polymyxin +
zinc bacitracin (P), (S), (T) |
ointment. |
|
permethrin (T) |
1% & 5% cream |
|
salicylic acid
(P), (S), (T) |
5% topical
solution/ lotion/gel. |
|
silver
sulphadiazine (P), (S), (T) |
1% cream |
|
sodium
thiosulfate (P), (S), (T) |
15% solution |
|
zinc oxide
(P), (S), (T) |
25%
cream/ointment |
12:
DIURETICS
|
amiloride (S),(T),
(4,7,8) |
5 mg tab.
(hydrochloride) |
|
furosemide
(P), (S), (T) |
20 & 40 mg
tab. 10mg inj. |
|
hydrochlorthiazide (S), (T) |
50 mg tab. |
|
mannitol (T) |
10% & 20% inj. |
|
spironolactone
(S), (T), (8) |
25 & 100 mg
tab. |
|
|
|
13:
GASTROINTESTINAL DRUGS
|
aluminium
hydroxide (P), (S), (T) |
500mg tablet |
|
|
320 mg/5ml
oral suspension |
|
aluminium
hydroxide + |
400 + 400 mg
tab. |
|
magenesium
hydroxide (P), (S), (T) |
200 + 200
mg/5ml susp. |
|
atropine
sulphate (P), (S), (T) |
1 mg tab. &
0.5mg inj. |
|
bisacodyl (P),
(S), (T) |
5mg tab |
|
cimetidine
(P), (S), (T) |
200 & 400mg
tab. 200mg inj |
|
cyclizine (P),
(S), (T) |
50mg tab. 12.5
mg/5ml syrup. 50mg inj. |
|
hyoscine
butylbromide (P), (S), (T) |
10 mg tab & 20
mg inj. |
|
ispaghulla
husk (P), (S), (T) |
for solution |
|
lactulose (T) |
50% syrup |
|
magnesium
hydroxide (P), (S), (T) |
550 mg/10ml
susp. 400 mg tab. |
|
metoclopramide
(P), (S), (T) |
10 mg tab.
10mg inj.
5mg / 5 ml
syrup |
|
omeprazole
(P), (S), (T) |
20 mg cap. |
|
oral
rehydration salt (P), (S), (T) |
components to
reconstitute 1 litre |
|
|
glucose/electrolyte solution: |
|
|
sodium
chloride 3.5g, trisodium |
|
|
citrate
dihydrate 2.9g, potassium |
|
|
chloride 1.5g,
glucose 20g. |
|
potassium
chloride (P), (S), (T) |
7.4% inj |
|
prochlorperazine (S), (T) |
5 mg tab. 12.5
mg inj. |
|
promethazine
(P), (S), (T) |
10 & 25mg
tablet. 1 mg/ml elixir. 25 mg/ml inj. |
|
sulphasalazine
(S), (T) |
500 mg tab. |
14:
HORMONES, OTHER ENDOCRINE DRUGS AND CONTRACEPTIVES
|
bromocriptine
(T) |
2.5 mg tab. |
|
carbimazole |
5mg tab. |
|
clomifene
(T,8) |
50 mg tablet |
|
condoms with
or without |
|
|
spermicide (nonoxinol)
(P), (S), (T) |
|
|
conjugated
estrogen (S), (T) |
0.625 mg / gm
cream |
|
dexamethasone
(P), (S), (T) |
0.5mg tab. 4 &
20 mg inj. |
|
diaphragms
with spermicide |
|
|
(nonoxinol)
(P), (S), (T) |
|
|
ethynylestradiol + levonorgestrol (S), (T) |
0.03 mg + 0.15
mg tab. |
|
ethynylestradiol + norethisterone (P), (S) |
(0.05 mg + 0.5
mg), (35 mcg + 1mg) tab. |
|
glibenclamide
(P), (S), (T) |
5 mg tab. |
|
human
chorionic |
1000 & 5000 iu
inj. |
|
gonadotrophic
hormone (T) |
|
|
hydrocortisone
(S), (T) |
100 & 250 mg
inj. |
|
17-hydroxyprogesterone caproate (S), (T) |
250 & 500 mg
inj. |
|
insulin comp. |
S100 IU/inj. |
|
zinc or
isophane (P), (S), (T) |
|
|
insulin
Regular (P), (S) , (T) |
100 IU. |
|
intrauterine device copper T (P),
(S), (T) |
|
|
levonorgesterol (P), (S) |
0.75
mg tab. |
|
metformin (P),
(S), (T) |
500 mg tab.
(as hydrochloride) |
|
norethisterone
(S), (T) |
5 mg tab. 200
mg inj. (as enanthate) |
|
oxytocin (S),
(T) |
10 units /ml; 1ml ampoule |
|
potassium
iodide (P), (S), (T) |
60 mg tablet |
|
prednisolone
(S), (T) |
5mg tablet |
|
propylthiouracil (T) |
50 & 100 mg
tab. |
|
thyroxine (T) |
50mcg tab. (as
sodium anhydrous) |
|
vasopressin/ADH
(T) |
20 IU/ inj. |
15:
IMMUNOLOGICALS
15.1
Diagnostics
15.2 Sera and
Immunologicals
|
anti-D
immunoglobulin (T) |
inj. |
|
antiscorpian
sera (P), (S), (T) |
inj. |
|
antivenom sera
(P), (S), (T) |
inj. |
|
diphtheria
antitoxin inj. (P), (S), (T) |
inj. |
|
hepatitis B
immunoglobulin (T) |
inj. |
|
tetanus
antitoxin (P), (S), (T) |
inj. |
|
tetanus toxid
(P), (S), (T) |
inj |
15.3 Vaccine
for Universal Immunization
|
BCG (dried)
vaccine (P), (S), (T) |
inj |
|
diptheria-pertussis tetanus vaccine (P), (S), (T) |
inj. |
|
dipatheria-tetanus
vaccine (P), (S), (T) |
inj. |
|
measles-mumps-rubella |
|
|
vaccine (P),
(S), (T) |
inj. |
|
measles
vaccine (P), (S), (T) |
inj. |
|
poliomyelitis
vaccine |
oral solution |
|
(live
attenuated) P), (S), (T) |
|
|
tetanus
vaccine (P), (S), (T) |
inj. |
15.4 Vaccines
for Specific Use.
|
hepatitis B
vaccine (T) |
inj. |
|
meningococcal
vaccine (T) |
inj. |
|
rabies vaccine
(P), (S), (T) |
inj. |
|
rubella
vaccine (T) |
inj |
|
yellow fever
vaccine (T) |
inj |
15.5
Immunosuppressents.
|
cyclosporin
(T), (10) |
50 mg/ml inj. |
|
|
25 & 100 mg
cap |
16:
MUSCLE RELAXANTS (PERIPHERALLY ACTING) AND CHOLINESTERASE
INHIBITORS
|
pyridostigmine (S),
(T), (8,10) |
60 mg tab. |
17:
OPHTHALMOLOGICAL PREPARATIONS
17.1
Anti-Infective Agents
|
acyclovir (T) |
3% eye oint. |
|
chloramphenicol (P), (S), (T) |
1% eye oint.
0.5% drops |
|
gentamicin
(S), (T) |
0.3% eye
drops/eye oint. |
|
ketoconazole
(T) |
2 mg/ml eye
drops |
|
polymixin B
sulphate + bacitracin zinc (S),(T) |
10,000 IU +
500 IU/gm oint. |
|
sulfacetamide
(P), (S), (T) |
10%, 20% & 30%
eye drops, 10% eye oint. |
|
tetracycline
(P), (S), (T) |
ointment.
|
17.2 Miotics
and Antiglaucoma Drugs.
|
dipivefrin (T) |
0.1% eye drops |
|
(levobunalol |
0.5% eye
drops) |
|
pilocarpine
(S) |
1%, 2% & 4%
eye drops. |
17.3
Mydriatics and Cycloplegics Drugs
|
atropine (S),
(T) |
1% & 2% eye
drops |
|
homatropine
(S), (T) |
2% eye drops |
|
phenylepherine
(T) |
0.12% eye
drops |
|
tropicamide
(S), (T) |
1% eye drops |
17.4
Corticosteroids
|
prednisolone
(T) |
0.2% eye drops |
17.5
Non-steroidal Antiallergic/Decongestants
|
antazoline
(S), (T) |
eye drops |
|
(naphazoline
(S), (T) |
eye drops) |
|
pheniramine
maleate (S), (T) |
eye drops |
|
zinc sulphate
+ boric acid (P), (S), (T) |
0.46% + 1.6%
eye drops |
17.6 Topical
Anaesthetics
|
oxybuprocaine
(S), (T) |
0.4% eye drops |
|
proparacaine
(S), (T) |
eye drops |
17.7 Others
|
artficial
tears (T) |
eye drops |
|
flourescine
sodium (S), (T) |
eye drops |
18: OXYTOCICS
AND ANTIOXYTOCICS
|
ergometrine
(P), (S), (T), (7) |
0.25mg tab.
(hydrogen maleate) 200 mg inj. |
19: PERITONEAL
DIALYSIS SOLUTION
|
intraperitonial dialysis parental solution |
|
|
(of
appropriate composition) (T) |
|
20:
PSYCHOTHERAPEUTIC DRUGS
|
amitryptyline
(S), (T) |
10, 25 & 50 mg
tab. |
|
chloral
hydrate(S), (T) |
1 g / 5ml
syrup |
|
chlorpromazine(S), (T) |
10, 25, 50
&100 mg tab. |
|
|
25 mg/5ml
syrup. 50 mg inj. |
|
clomipramine
(T) |
10 & 25 mg
cap.(as hydrochloride) |
|
diazepam
(P,2), (S), (T) |
2, 5 & 10 mg
tab. 10mg inj |
|
fluoxetine
(S), (T) |
20 mg cap. |
|
fluphenazine
(S), (T) |
25 mg inj (as
decanoate) |
|
haloperidol
(P), (S), (T) |
0.25, 1.25 &
5 mg tab
5mg inj.
2mg/ml oral drops |
|
imipramine (S) |
25 mg tab. |
|
lithium
carbonate (T) |
400 mg tab. |
|
resperidone
(S), (T) |
1 mg, 2 mg, 3
mg tab. |
|
trifluperazine
(P), (S), (T) |
5 mg tab. |
21:
DRUGS ACTING ON THE RESPIRATORY TRACT
|
aminophylline
(P), (S), (T), (10) |
100 & 200 mg
tab. 250 mg inj. |
|
baclomethasone
(S), (T) |
250 mcg
aerosol(as dipropionate) |
|
cromoglycate
(T) |
1mg/dose
aerosol (as disodium) 20 mg cap. (as disodium) |
|
dextromethorphan compound (P), (S), (T) |
Syrup |
|
epinephrine
(P), (S), (T) |
1 mg inj. |
|
salbutamol
(P), (S), (T), (10) |
2 & 4 mg tab.
2mg/5ml syrup,100 mcg/dose aerosol(T), 50mcg/5ml inj. |
|
|
5mg (as
sulfate)/ml respirator solution for use in nebulizers, |
|
theophylline
(P), (S), (T), (11) |
180 & 270 mg
tab. 350 mg tab.
(S.R) 120
mg/5ml syrup. |
22: SOLUTIONS
CORRECTING WATER,
ELECTROLYTE AND ACID BASE DISTURBANCES
|
dextrose +
saline (P), (S), (T) |
10% + 0.9% IV
solution, 5% + 0.45% IV solution, 4.3% + 0.18% IV solution, 3%
+ 0.3% IV solution |
|
dextran 40
(P), (S), (T) |
IV solution |
|
dextrose (P),
(S), (T) |
5%, 10% & 25%
IV solution |
|
normal saline
(P), (S), (T) |
0.9% & 0.45%
IV solution |
|
potassium
chloride (P), (S), (T) |
500 mg tab.
7.4% IV solution |
|
ringer’s
lactate (P), (S), (T) |
IV solution |
|
sodium
bicarbonate (P), (S), (T) |
0.7% IV
solution |
|
water for inj.
(P), (S), (T) |
|
23: VITAMINS AND
MINERALS
|
ascorbic acid
(P), (S), (T) |
100 mg tab. |
|
calcium
gluconate (P), (S), (T) |
100 mg/ml inj. |
|
calcium
lactate (P)¸ (S), (T) |
10 mg tab. |
|
D – 3 (S),
(T) |
300000 &
600000 Units |
|
erogocalciferol (P), (S), (T) |
1.25 mg (50
000 IU) capsule/tablet, 250 ug/ml (10 000 IU/ml) oral solution |
|
hexavitamin
USP (P), (S), (T) |
tab. each tab.
contains not less than:
Vitamin A 5000IU, Vitamin D 400IU
Ascorbic Acid 75mg, Thiamine Hydrochloride 2mg, Riboflavin 3mg,
Nicotinamide 20 mg. |
|
nicotinamide
(P), (S), (T) |
50 mg tab. |
|
pyridoxin (P),
(S), (T) |
25 mg tab. (as
hydrochloride) |
|
retinol (P),
(S), (T) |
10000 IU tab.
100,000 IU inj. |
|
thiamine (P),
(S), (T) |
100mg/ml inj.
(as hydrochloride) 100mg tab. (as hydrochloride) |
24: E.N.T.
PREPARATIONS
|
boroglycerine
(P)¸ (S), (T) |
40% |
|
clotrimazole
(T) |
1% topical
solution |
|
ephedrine
nasal drops (P), (S), (T) |
0.5% |
|
gentamycin +
hydrocortisone (T) |
3% + 0.1% |
|
gentian violet
(P), (S), (T) |
0.5% |
|
ichthamol
glycerin BPC (P), (S), (T) |
|
|
polymyxin B
sulphate + |
10,000 IU +
50mg/ml ear drops |
|
lignocaine
hydrochloride (P), (S), (T) |
|
|
prednisolone
(T) |
nasal drops.
5mg tab. |
|
prochlorperazine (P), (S), (T) |
5 mg tab. |
|
promethazine
(P), (S), (T) |
10 & 25 mg
tab. |
|
|
1mg/ml elixir.
25mg inj. |
|
pseudoephedrine |
tab/syrup |
|
compound
(S),(3) |
|
|
soda glycrine
BPC (P), (S), (T) |
|
|
xylocaine (P),
(S), (T) |
2% inj. 4%
topical solution, 2% topical gel |
|
xylocaine +
adrenaline (T) |
2% + 1:80,000,
2% + 1:200,000 |
|
xylometazoline
(P), (S), (T) |
0.1% nasal
drops |
25: ANTISEPTICS
AND DIS-INFECTANTS
25.1
Antiseptics
|
chlorhexidine
gluconate (P), (S), (T) |
1.5% solution |
|
chloroxylenol
(P), (S), (T) |
4.8% solution |
|
glutaraldehyde
(T) |
10% solution |
|
glutoral |
2% solution) |
|
hydrogen
peroxide BP.(P), (S), (T) |
solution |
|
povidone
iodine (P), (S), (T) |
7.5% solution |
|
tincture
benzoin co. BP (P), (S), (T) |
|
|
tincture
iodine (P), (S), (T) |
|
25.2
Disinfectants
|
calcium
hypochlorite (T) |
powder for
solution |
26: DENTAL
PREPARATIONS (T)
|
acidulated
phosphate fluoride gel |
|
calcium
hydroxide paste |
|
camphorated
monochlorophenol. |
|
eugenol, also
with fillers |
|
formocresol
(formaldehyde 19% cresol 35% and glycerol 15%) |
|
iodoform
compound paint |
|
mercury |
|
silver alloys |
|
sodium flouride drop/rinse/tab |
|
tannic acid
powder |
|
triamcinolone
acetonide paste |
|
zinc oxide +
magnesium oxide in polyacrylic 40% cement. |
27: DISPENSARY
ITEMS: (P), (S), (T)
|
coal tar |
|
cresol |
|
emulsifying
wax |
|
formaldehyde |
|
gentian violet |
|
glucose |
|
glycerin |
|
hexylresorcinol throat paint |
|
hydrogen
peroxide |
|
iodine |
|
kaolin |
|
linolic acid |
|
liquid
paraffin |
|
magnesium
sulphate |
|
methylated
spirit |
|
paraffin, hard |
|
paraffin,
yellow |
|
pectin |
|
peppermint oil |
|
potassium
chloride |
|
potassium
permanganate |
|
salicylic acid |
|
sodium acid
citrate |
|
sodium
bicarbonate |
|
soft paraffin
wax |
|
sulfer sublime |
|
tannic acid |
|
tragacanth |
|
trisodium
citrate dehydrate |
|
turpentine oil |
|
wool fat |
|
zinc oxide
powder |
|
zinc
undeconate |
28: DRUGS FOR
LOCAL PURCHASE
|
Drugs in the
following groups are required occasionally. Therefore drugs in
these groups can be made available through local purchase by
hospitals. Some of the illustrative drugs in these groups are
mentioned below:- |
28.1 ANTIDOTES
AND OTHER SUBSTANCES USED IN POISONING
|
atropine (P),
(S), (T) |
2mg/ml inj.
(as sulfate) |
|
charcoal,
activated (P), (S), (T) |
powder |
|
desferrioxamine (S), (T) |
500mg inj. (as
mesylate) |
|
dimercaprol
(S), (T) |
100 mg inj. |
|
flumazenil
(P), (S), (T) |
500 mcg inj. |
|
magnesium
sulphate (S,T) |
50% inj. |
|
methionine
(S), (T) |
250 mg tab.
(as racemate) |
|
naloxone (P),
(S), (T) |
0.04 & 0.4 mg
inj. (as hydrochloride) |
|
neostigmine
(T) |
15 mg tab. (as
bromide) 0.5mg inj. (methyl sulphate) |
|
obidoxime (T) |
250 mg inj.
(as chloride) |
|
penicillamine
(T) |
125 & 250 mg
capsule or tablet, |
|
physostigmine
(T) |
1 mg inj. (salicylate) |
|
pralidoxime
(T) |
200 mg/ml Inj. |
|
protamine (T) |
10 mg inj. (as
sulphate) |
|
prussian blue
(T) |
powder for
topical use |
|
sodium calcium
edetate (T) |
1 gm inj. |
|
sodium nitrite
(T) |
300 mg inj. |
|
sodium
thiosulfate (T) |
500mg/ml inj. in 50 ml ampoule. |
28.2
Antileprosy Drugs
|
clofazimine
(T) |
100 mg cap. |
|
dapsone (T) |
50 mg tab. |
28.3 ANTI-NEOPLASTICS,
IMMUNOSUPPRESSIVES AND DRUGS USED IN PALLIATIVE CARE
28.3.1
Immunosuppressive Drugs
|
asparaginase
(T), (10) |
10,000 iu inj. |
|
aminogluthemide |
tab. |
|
anastrazole(T)
|
1 mg tab. |
|
azathioprine
(S), (T), (10) |
50 mg tablet |
|
|
100 mg inj.
(as sodium salt) |
|
bleomycin (T),
(10) |
15 mg inj. (as
sulphate). |
|
busulphan (T) |
0.5mg tab. |
|
calcium
folinate (T), (10) |
15 mg tablet,
30 mg inj. |
|
carboplatin
(T) |
150 mg & 450
mg inj. |
|
chlorambucil
(S), (T), (10) |
2 mg tab. |
|
chlormethine
(T), (10) |
10 mg inj. (as
hydrochloride) |
|
cisplatin (T),
(10) |
10, 25 & 50
mg inj. |
|
cyclophosphamide (T), (10) |
50 mg tablet
200, 500 mg & 1 gm inj. |
|
cyproterone
acetate (T) |
50 mg tab. |
|
cytarabine
(T), (10) |
100 mg inj. |
|
dacarbazine
(T), (10) |
200 mg inj. |
|
dactinomycin
(T), (10) |
0.5mg inj |
|
di-ethylstilboestrol diphosphate sodium (S),(T) |
1mg tab. |
|
doxorubicin
(T), (10) |
10 & 50 mg inj. |
|
etoposide (T) |
100mg cap. |
|
|
100mg inj. |
|
flutamide (S),
(T), (10) |
250 mg tab |
|
5-fluorouracil
(T) |
250 mg inj. |
|
hydroxyurea
(S), (T) |
500 mg cap. |
|
ifosfamide (T) |
inj. |
|
lomustine (T) |
cap. |
|
medroxyprogesterone (T) |
100 mg tab.
150 mg inj. |
|
megesterol
acetate |
2mg tab. |
|
mesna (T) |
400 mg inj. |
|
melphalan (T) |
100 mg inj. |
|
mercaptopurine
(T), (10) |
50mg tablet |
|
methotrexate
(T), (10) |
2.5, 5 & 10 mg
tab. 5, 50 & 500 mg inj. |
|
mitomycin (T) |
inj |
|
mitozantrone
(T) |
inj |
|
procarbazine
(T) |
50mg cap. (as
hydrochloride) |
|
tamoxifen (S),
(T) |
10 & 20 mg tab |
|
6 thioguanine
(T) |
40 mg tab. |
|
vincristine
(T), (10) |
1 & 5 mg inj.
(as sulfate) |
|
vinblastine
(T), (10) |
inj |
|
vinorelbine
(T) |
10 & 50 mg inj. |
28.4 DIAGNOSTIC
AGENTS
|
barium
sulphate (S), (T) |
powder for
oral use |
|
iodinated
poppy |
|
|
iodipamide (T) |
50% inj. |
|
iohexol (T) |
180 & 300
mg/ml inj |
|
iophendylate
(T) |
30.5% inj. |
|
iothalamate
(T) |
60% aqueous
solution |
|
meglumine
diatrizoate BP/USP (T) |
inj. |
|
meglumine
diatrizoate+ |
66% + 10% inj |
|
sodium
diatrizoate (T) |
|
|
meglumine
iotroxenate (T) |
0.105% & 1.26%
solution for inj. |
|
meglumine
ioxagalate |
39% + 19.65%
inj. |
|
+sodium
ioxagalate (T) |
|
|
propyliodone
(T) |
10 gm inj |
|
seed oil (T) |
inj. |
|
sodium
acetrizoate (T) |
40% inj |
|
sodium ipodate
(T) |
500 mg
cap. |
29: DRUGS
FOR SPECIALIZED CENTERS
29.1
Antiretroviral drugs
|
didanosine (DDI),
(T) |
buffered
chewable, dispersible tablets 25mg, 50mg, 100mg, 150mg, 200mg,
buffered powder for oral solution 100mg, 167mg, 250mg packets,
unbuffered enteric coated capsule 125mg, 200mg, 250mg, 400mg. |
|
efavirenz (T) |
capsule 50mg,
100mg, 200mg, oral solution 150mg/5ml |
|
indinavir (T) |
capsule 200mg,
333mg, 400mg, (as sulfate) |
|
lamivudine
(3TC), (T) |
tablet 150mg,
oral solution 50mg/5ml |
|
nelfinavir (T) |
tablet 250mg
(as mesilate) |
|
nevirapine (T) |
tablets 200mg,
oral suspension 50mg/5ml |
|
ritonavir (T) |
capsule 100mg,
oral solution 400mg/5ml |
|
saquinavir (T) |
capsule 200mg |
|
stavudine
(D4T), (T) |
capsule 15mg,
20mg, 30mg, 40mg, powder for oral solution 5mg/5ml |
|
zalcitabine (DDC),
(T) |
tablets
0.375mg, 0.75mg |
|
zidovudine (ZDV),
(T) |
tablet 300 mg,
capsule 100mg, oral solution or syp. 50mg/5ml solution, for IV
infusion injection 10mg/ml in 20ml vial. |
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